- Richard Malcolm Johnston Legal Document (Transfer of Enslaved Persons), 18591
- Ride Boldly Ride, by President Reade1
- Rochambeau Map Collection1
- Samuel Hugh Hawkins diary, January-July 18771
- Samuel Meeker letter to General James Winchester1
- Samuel Worcester letters to Reverend William Jenks, circa 18151
- Scott Pope, Clifford H. (Baldy) Baldowski Editorial Cartoon [MLK, Jr. with American Flag]1
- Scrapbook, Dalton, Ga. Bedspread Center of the World, Dalton, Georgia, 1948-19491
- Seaborn J. Mays papers1
- Second Seminole War, Okefenokee region manuscript map1
- Sidney Swinney letter to Lord George Townshend1
- Sir Patrick Houston letter1
- Slaves and the Courts, 1740 to 18601
- Sons of Temperance Ledger1
- South Georgia Folklife Collection1
- Southern Photographs Collection1
- Southern Polytechnic State University: The History1
- State of Georgia bond1
- Stewart family genealogy1
- Swainsboro, Georgia city directories1