- Collection:
- Georgia Government Publications
- Serial:
- Antimicrobial susceptibilities of selected pathogens / Georgia Public Health.
- Title:
- Antimicrobial susceptibilities of selected pathogens, 2001 / Georgia Public Health
- Creator:
- Georgia. Division of Public Health
- Contributor to Resource:
- Georgia. Division of Public Health.
- Publisher:
- [Atlanta, GA] : Georgia Public Health, 2001
- Date of Original:
- 2001
- Subject:
- Pathogenic microorganisms--Georgia
Microbial sensitivity tes
Antibiotics--Side effects--Georgia - Location:
- United States, Georgia, 32.75042, -83.50018
- Medium:
- state government records
- Type:
- Text
- Format:
- application/pdf
- Description:
- Title from caption
"B-lactam antibiotics and other antibiotics."
"Trends, comments, and other pathogens." - External Identifiers:
- Call Number GA H800.P8 S1 A5 2001
- Metadata URL:
- https://dlg.galileo.usg.edu/id:dlg_ggpd_y-ga-bh800-pp8-bs1-ba5-b2001-belec-p-btext
- Digital Object URL:
- https://dlg.galileo.usg.edu/do:dlg_ggpd_y-ga-bh800-pp8-bs1-ba5-b2001-belec-p-btext
- Language:
- eng
- Holding Institution:
- University of Georgia. Map and Government Information Library
- Rights:
-
Campylobacter spp.* * (One weekly isolate from stewide convenience sample tested at CDC). Salmonella spp. (non-typhoidal) (~10% sample of statewide isolates tested at CDC). Shigella sonnei (All available statewide isolates tested at GPHL). Shigella flexneri (All available statewide isolates tested at GPHL). E. coli O157 (All available statewide isolates tested at CDC). Streptococcus pneumoniae (All invasive isolates from Atlanta (20-cty) MSA tested at CDC). Mycobacterium tuberculosis (All statewide isolates tested at GPHL).
Antimicrobial Susceptibilities of Selected Pathogens, 2001
B-lactam antibiotics
Number tested
53
185
406
47
27
665
428
Total isolates
640
1721
629
70
45
746
452
Percent Tested (%)
8
11
65
67
60
89
95
% Susceptible
amoxicillin
89
amoxicillin-clavulanic acid
98
47
26
100
ampicillin
87
4
15
96
cefotaxime
83
cefoxitin
>99
100
ceftiofur
>99
100
ceftriaxone
>99
>99
100
100
cefuroxime sodium
72
cephalothin
>99
32
81
100
imipenem
100
100
meropenem
78
penicillin
68
azithromycin
96
erythromycin
96
73
nalidixic acid
74
99
>99
96
ciprofloxacin
74
100
>99
98
100
levofloxacin
99
amikacin
100
100
gentamicin chloramphenicol clindamycin
100
98
>99
98
100
100
90
96
32
100
96
96
94
apramycin
100
100
kanamycin
94
100
streptomycin
83
58
2
100
tetracycline
66
82
79
9
90
sulfamethoxazole
85
79
45
100
trimethoprim/sulfamethoxazole
98
83
60
100
62
vancomycin
100
ethambutol
99
isoniazid
94
rifampin
>99
99
other antibiotics
Trends, Comments and Other Pathogens
Campylobacter Susceptibilities were determined using 2001 NCCLS breakpoints for Enterobacteriaceae. Erythromycin susceptible: MIC < 4
spp.
g/ml.
Salmonella spp. Antimicrobial treatment for enteric salmonellosis generally is not recommended.
Antimicrobial resistance in S. sonnei is dynamic. In 2000, nearly half of isolates were resistant to trimethoprimShigella sonnei sulfamethoxazole (SXT). In 2001 this changed, with large outbreaks among children caused by a strain with SXT-
susceptibility.
Shigella flexneri E. coli O157
S. flexneri has been associated with outbreaks among men who have sex with men. Use of antimicrobials is controversial for enteritis caused by E. col i O157. Several studies have shown no symptomatic improvement and increased risk for hemolytic-uremic syndrome among treated patients (Guerrant RL et. al. Clin Infect Dis 2001; 32:331-51).
Streptococcus Pneumoniae
NCCLS 2001 MIC interpretive standards for S. pneumoniae were used for all antimicrobials. For penicillin, 16% (109/665) had intermediate susceptibility and 16% (106/665) were resistant (penicillin MIC breakpoints: susceptible <0.06 g/ml, intermediate 0.12-1 g/ml, resistant >2 g/ml). For amoxicillin, 6% (37/665) were intermediate and 5% (34/665) were resistant (amoxicillin MIC breakpoints: susceptible <2 g/ml, intermediate 4 g/ml, resistant >8 g/ml). For cefuroxime, <1% (1/665) were intermediate and 28% (184/665) were resistant (cefuroxime MIC breakpoints: susceptible <0.5 g/ml, intermediate 1 g/ml, resistant >2 g/ml). For cefotaxime, 14% (94/665) were intermediate and 3% (22/665) were resistant (cefotaxime MIC breakpoints: susceptible <0.5 g/ml, intermediate 1 g/ml, resistant >2 g/ml). For meropenem, 10% (68/665) were intermediate and 12% (78/665) were resistant (meropenem MIC breakpoints: susceptible <0.25 g/ml, intermediate 0.5 g/ml, resistant >1 g/ml). Five isolates (<1%) were resistant to levofloxacin. All isolates were susceptible to vancomycin.
Mycobacterium 6% (27/427) were INH-resistant. Two cases of multidrug-resistant TB (resistant to at least INH and rifampin) were identified, tuberculosis both among foreign-born persons.