- Port of Savannah Slave Manifests1
- President Jimmy Carter Daily Diary1
- Record book of the Sardis Church of Christ 1
- Records of the Bureau of Indian Affairs, 1793 - 1999, Subject Numeric Correspondence Files, 6/14/1914 - 6/19261
- Records of the Bureau of Prisons, 1870 - 20091
- Rencher Nicholas Harris papers, 1851-1980 and undated, bulk 1926-19651
- Rochambeau Map Collection1
- Samuel Meeker letter to General James Winchester1
- Savannah Biographies1
- Scott Pope, Clifford H. (Baldy) Baldowski Editorial Cartoon [MLK, Jr. with American Flag]1
- Seaborn J. Mays papers1
- Second Seminole War, Okefenokee region manuscript map1
- Sidney Swinney letter to Lord George Townshend1
- Sir Patrick Houston letter1
- Slave bills of sale1
- Slaves and the Courts, 1740 to 18601
- Sons of Temperance Ledger1
- Southern Labor Archives1
- Southline Press, Inc. Photographs1
- Standard Telephone Company records1
