From Preconception
A Regional Look at Periods of Risk for Georgia's Newborns
To Infant Protection
Acknowledgements
Georgia Department of Public Health: Brenda Fitzgerald, M.D., Commissioner Division of Health Promotion: Yvette Daniels, J.D., Director Maternal and Child Health Program (MCH): Seema Csukas, M.D., Ph.D., Interim Director MCH Epidemiology Office: Theresa Chapple-McGruder, Ph.D., M.P.H., Director Commissioner's Office: Chief of Staff Office of Health Indicators for Planning Cobb/Douglas Health District Porter Novelli Healthcare Georgia Foundation
Suggested Citation: Theresa Chapple-McGruder, Ph.D., Yueqin Zhou, M.A., Gordon Freymann, M.P.H., Brian Castrucci, M.A. From Preconception to Infant Protection. Georgia Department of Public Health, Maternal and Child Health Program, Office of Epidemiology, March 2012.
"From Preconception to Infant Protection" was funded in part by a grant from Healthcare Georgia Foundation.
Dear Fellow Georgians,
The Georgia Department of Public Health became its own agency July 1, 2011 and immediately began tackling issues to improve the health of Georgia's communities and its entire population. One of these issues is infant mortality. The number of infant deaths within a community can be one of the best measures of health status and, sadly, Georgia's infant mortality rate is higher than the national average.
In this publication, "From Preconception to Infant Protection: A Regional Look at Periods of Risk for Georgia's Newborns," we provide an in-depth analysis of the causes of infant mortality in Georgia and identify specific clusters throughout the state where most infant deaths occur.
It is our hope that this report provides you with a framework for understanding the problem and specific interventions to address these issues. This is our call to action to work together to reduce infant mortality and protect the health and well-being of families in our communities.
Success in meeting our priorities requires forging strong relationships among stakeholders, maximizing current programs and resources, and developing innovative initiatives. The Maternal and Child Health Program in the Georgia Department of Public Health will begin working with communities to significantly reduce infant mortality. I look forward to your partnership.
Sincerely,
Brenda Fitzgerald, MD Commissioner and State Health Officer Georgia Department of Public Health
Table of Contents
Introduction
1
Key Findings
3
Infant Mortality at the State Level
4
Infant Mortality at the Community Level
Fulton, Douglas, Cobb, Clayton (Cluster A)
14
Bibb, Twiggs, Houston, Jones (Cluster B)
15
Muscogee, Chattahoochee (Cluster C)
16
Lowndes (Cluster D)
17
Richmond (Cluster E)
18
Chatham (Cluster F)
19
Perinatal Periods of Risk
20
Fulton, Douglas, Cobb, Clayton (Cluster A)
22
Bibb, Twiggs, Houston, Jones (Cluster B)
23
Muscogee, Chattahoochee (Cluster C)
24
Lowndes (Cluster D)
25
Richmond (Cluster E)
26
Chatham (Cluster F)
27
Implications for Georgia
28
Methods
30
Data
34
Definitions
43
From 2002-2006, an infant died in Georgia every
7 hours and 36 minutes.
The number of infant deaths within a community can be one of the best measures of health status and is reflected in a community's infant mortality rate (IMR). The IMR is defined as the number of infant deaths in the first year of life per 1,000 live births. From 2002 through 2006, the IMR for Georgia was 8.4 infant deaths per 1,000 live births. For the same time period, the US IMR decreased by 10% while Georgia's IMR remained 15% to 20% greater than the national average and 42% higher than the Healthy People 2010 goal of reducing the average to 4.5 deaths per 1,000 live births. Infants who were Black, non-Hispanic experienced an IMR nearly two and a half times higher than infants who were White, non-Hispanic. When considering all Georgia births, two-thirds of infant deaths happened in the first 28 days of life, 54% of which occurred within the first week of life.
1
In an effort to understand Georgia's IMR--a key first step in addressing the issues that contribute to it--this report details an analysis of the statewide picture of infant mortality in Georgia and within Georgia's 18 public health districts and 159 counties and explores infant mortality clusters that exist outside of administrative boundaries within the state such as county, zip code and census tract. Further analyses outline geographical areas with disproportionally high IMR and excess death resulting from health and other factors from preconception through the first birthday, known as the perinatal periods of risk (PPOR) model. These analyses are provided to support targeted interventions as an effective means to reduce the state's IMR.
2
Key Findings
In Georgia, the number one cause of infant mortality is disorders related to preterm birth and low birth weight.
The three public health districts with the highest rates of infant mortality are: North Central, West Central and South.
Analysis of the infant mortality rate ratio at the county level reveals concentrated areas of infant deaths that are disguised in health district level analyses. Smaller geographical level analyses aid in understanding areas and communities with high IMRs otherwise masked by examination from a county or district level.
Six significant clusters of infant deaths were found across the state: Cluster A: Fulton, Douglas, Cobb and Clayton Counties Cluster B: Bibb, Twiggs, Houston and Jones Counties Cluster C: Muscogee and Chattahoochee Counties Cluster D: Lowndes County Cluster E: Richmond County Cluster F: Chatham County
In the region surrounding Lowndes County (Cluster D), the infant mortality rate was three times the national average; Richmond and Chatham Counties (Clusters E and F) were twice the national average.
In the region of Bibb, Twiggs, Houston and Jones Counties (Cluster B), respiratory distress was the leading cause of death; this was the fifth leading cause statewide.
Across all clusters studied, women were nearly two times less likely to have had adequate prenatal care compared to women whose infants celebrated a first birthday.
Each of the six identified clusters is characterized by demographic information, causes of infant death, demographic and behavioral factors related to infant death and a PPOR analysis. Appropriate interventions to address the unique characteristics of infant mortality in each cluster are outlined.
3
infant mortality in georgia
Georgia's infant mortality rate decreased from 8.7 infant deaths per 1000 live births in 2002 to 7.8 per 1000 in 2006. While most races experienced a decline in infant mortality rates, it did little to impact the existence of racial/ethnic disparities. Black non-Hispanics experienced an infant mortality rate nearly two and a half times higher than White non-Hispanics (See Figure 1). Two-thirds of infant deaths happen in the neonatal period, 54% of which occur within the first week of life (Figure 2).
Figure 1. Infant mortality by race/ethnicity, Georgia, 20022006
16 14
12 10
RATE
8
6
4
2
0 2002
2003
2004 2005
2006
YEAR
Rates are infant (under 1 year) deaths per 1,000 live births. All racial groups are exclusive of the Hispanic ethnicity.
State White Black Hispanic Other
"Black non-Hispanics experienced an infant mortality rate nearly TWO & A HALF TIMES HIGHER than White non-Hispanics."
Figure 2. Percent of early neonatal, neonatal, and postneonatal deaths,
Georgia, 20022006
12.8
33.4
53.8
Early Neonatal Death (07 Days)
Neonatal Death (827 Days)
Postneonatal Death (28364 Days)
4
The top 10 causes of infant death are outlined in Table 1. In Georgia, the leading 10 causes account for 70% of the infant deaths; while the top three causes account for nearly 50% of all infant deaths. While the leading three causes of infant death are the same for Georgia and the Nation, the order differs. The number one cause of infant mortality for the Nation is congenital malformations, deformations, and chromosomal abnormalities, and for Georgia it is disorders related to preterm birth and low birth weight.
Table 1. Infant mortality rates for the 10 leading causes of infant death, Georgia, 20022006
Causes of death
Number
% of total Mortality
deaths
rate
All causes
5743
100
8.24
Disorders related to short gestation
1117
19.5
1.62
and low birth weight, not elsewhere
classified
Congenital malformations, deformations and chromosomal abnormalities
964
16.8
1.39
Sudden infant death syndrome
621
10.8
0.90
Newborn affected by complications of
321
5.6
0.46
pregnancy
Respiratory distress of newborn
245
4.3
0.35
Accidental/unintentional injuries
181
3.2
0.26
Bacterial sepsis of newborn
169
2.9
0.24
Newborn affected by complications of
164
2.9
0.24
placenta, cord and membranes
Mecrotizing enterocolitis of newborn
134
2.3
0.19
Disease of circulatory system
131
2.3
0.19
Rates are infant (under 1 year) deaths per 1,000 live births.
Rank -- 1
2
3 4
5 6 7 8
9 10
5
"In Georgia, the leading causes of infant death are disorders related to preterm birth & low birth weight."
6
Figure 3. Georgia's public health districts
Georgia is divided into 159 counties that are aggregated into 18 Public Health Districts (PHDs)
7
INTERPRETATION of MAPS
Blue and white areas on the following maps should be interpreted as areas with infant mortality rates less than the state's average. The tan color represents areas that have infant mortality rates similar to the state's. The dark orange and red represents areas that have higher infant mortality rates than the state. For the first two maps, the comparisons are made between the state's IMR and the public health district or county. The remaining maps are based on Standardized Mortality Ratios.
Rate ratio of infant deaths by public health Figure 4. district compared to the state average,
Georgia 20022006
01-1
01-2
02-0
03-1 03-2
03-4 03-5
03-3
10-0
04-0
05-2
IM Rate Ratios by Public Health District
0.678571 - 0.785714 0.892857 - 0.976190 1.035714 - 1.107143 1.190476 - 1.285714 1.345238 - 1.452381
06-0
07-0 08-2
05-1
08-1
09-2
09-1
8
The five year infant mortality rates (IMR) range from 5.7 to 12.2 per 1,000 live births across Georgia's 18 PHDs. Figure 5 displays the variance in rate ratios of the district infant mortality rates compared to the overall state rate of 8.24 per 1,000 live births. North Central, West Central and South health districts have the highest IMR compared to the state. Research has documented that having lower educational attainment, increased
poverty and being a member of a minority racial ethnic group places individuals at higher risk for poor birth outcomes. The PHD with the highest IMR had a poverty rate of twenty percent or greater compared to seventeen percent for the state. Those districts also had the highest percent of non-white racial/ethnic groups. The percent of educational attainment beyond high school varied by district, over eighty percent of residents
in Fulton, East Metro and DeKalb health districts have a high school education or higher compared to 71 percent for the state. South and West Central health districts have infant mortality rates exceeding 11 per 1,000 live births; greater than twenty percent of its residents below poverty and one-third of its residents attaining less than a high school education.
Rate ratio of infant deaths by Figure 5. county compared to State average,
Georgia 20022006
Dade
Catoosa
Walker
Whitfield
Murray
Chattooga Floyd
Gordon Bartow
Fannin
Union
Towns
Rabun
Gilmer Pickens Cherokee
Lumpkin
White
Habersham Stephens
Dawson Forsyth
Banks
Franklin
Hall
Jackson
Madison
Hart Elbert
IM Rate Ratios by County
0.000000 - 0.357143 0.440476 - 0.964286 1.000000 - 1.380952 1.392857 - 1.940476 2.297619 - 3.440476
Polk Haralson
Carroll Heard
Paulding Douglas
Coweta
Cobb
Gwinnett
Barrow
Clarke
DeKalb
Walton
Oconee
Fulton Clayton
Fayette
Rockdale
Henry
Newton
Morgan
Oglethorpe
Wilkes
Lincoln
Greene
Taliaferro McDuffie
Warren
Spalding
Butts
Jasper
Putnam
Hancock
Glascock
Columbia Richmond
Troup
Meriwether
Pike
Lamar
Monroe
Jones
Baldwin
Harris
Upson
Talbot
Crawford
Bibb
Twiggs
Wilkinson
Washington
Jefferson
Johnson
Burke
Jenkins
Screven
Muscogee
Taylor
Chattahoochee
Marion
Schley
Macon
Stewart
Webster
Sumter
Quitman
Randolph
Terrell
Lee
Clay
Calhoun
Dougherty
Peach Houston
Bleckley
Dooly
Pulaski
Dodge
Crisp
Wilcox
Turner
Worth Tift
Ben Hill Irwin
Laurens
Emanuel
Treutlen
Candler
Bulloch
Effingham
Wheeler Montgomery Toombs
Evans Tattnall
Telfair Jeff Davis
Appling
Long
Bryan Liberty
Chatham Chatham
Coffee
Bacon
Wayne
McIntosh McIntosh
Early
Baker
Miller
Mitchell
Colquitt
Berrien Cook
Atkinson
Pierce Brantley
Glynn
Glynn
Lanier
Ware
Seminole
Decatur
Grady
Thomas
Brooks
Lowndes
Clinch
Charlton
Camden
Camden
Echols
Figure 5. Illustrates analysis of the infant mortality rate ratio at the county level that reveals concentrated areas of infant deaths that were previously disguised in figure 4 by district level aggregation
9
Figure 6. Sub-county level standardized infant mortality ratio
Figure 6. Illustrates the standardized infant mortality rate ratio (observed number of infant deaths divided by the expected number of infant deaths) per one square mile
Analyzing infant deaths at small geographical levels aids in understanding areas and communities with high infant mortality rates as aggregating at high levels mask differences that occur at the local level. As depicted in this map, areas with high infant mortality rates can cross county lines (Quitman, Randolph and Clay) or may be relegated to small distinct community areas within a county (Richmond, Bibb).
Georgia, 20022006
10
Figure 7. Significant infant mortality clusters
Using methods described on page 30, six significant clusters of infant deaths were found across the state displayed in Figure 7.
Note the area with the densest concentration of infant deaths was not identified to be a cluster. This may be due to the parameters placed on the statistical test stating that a cluster could not be larger than 10 square miles or include more than 10% of the population. Table 2 provides demographic data on the clusters.
Georgia, 20022006
11
Figure 8.
Significant clusters of neonatal mortality
This map displays seven clusters of neonatal mortality.
Notably, six of the seven clusters are the same as the infant mortality clusters. The cluster in DeKalb County is the only cluster that was not significant when examining infant death as a whole.
Georgia, 19972006
12
Figure 9.
Significant clusters of postneonatal mortality
Four significant clusters of postneonatal deaths were found across the state, all of which were in existing clusters of infant death.
Notable, significant postneonatal clusters were not found in Chatham or Richmond, suggesting that the infant death rates in these areas are driven mainly by the neonatal death rate.
Georgia, 19972006
13
Cluster A Fulton, Douglas, Cobb and Clayton
Cluster A covers a portion of 86 census tracts, 24 zip codes, and 4 counties (Fulton, Douglas, Cobb and Clayton). With a population nearing 360,000, this cluster has the lowest five year infant mortality rate of all the clusters at 11.8 infant deaths per 1000 live births (see Table 2 for detailed population characteristics).
The three leading causes of infant death within this cluster mirror the leading causes of infant death for the state (see tables 1 and 3), with more than 20% of the infants dying from disorders related to preterm birth and low birth weight.
Causes of death
Number % of total Mortality
deaths
rate
All causes
337 100.0
11.8
Disorders related to
69
short gestation and
low birth weight, not
elsewhere classified
20.5
2.44
Congenital malformations 50
14.8
1.77
and chromosomal
abnormalities
Sudden infant
42
12.5
1.49
death syndrome
Rank
Rates are infant (under 1 year) deaths per 1,000 live births.
In examining demographic and behavioral factors related to infant death, women who experience an infant death are:
The same age as women in the cluster whose infants survive to age 1
Less likely to have more than a high school degree compared to women in the cluster whose infants survive to age 1 (24.9% vs. 31.8%)
Three times less likely to be White non-Hispanic or Hispanic compared to women in the cluster whose infants survive to age 1
Less likely to be married compared to women in the cluster whose infants survive to age 1 (24.3% vs. 32.1%)
More likely to be smokers (5.9% vs. 3.8%) and have had previous adverse birth outcomes (2.1% vs. 0.7%) compared to women in the cluster whose infants survive to age 1
Two times less likely to have had adequate prenatal care compared to women in the cluster whose infants survive to age 1 See Tables 4-6 for other within group comparisons as well as comparisons to the state.
14
Cluster B Bibb, Twiggs, Houston and Jones
Cluster B covers a portion of 36 census tracts, 17 zip codes, and 4 counties (Bibb, Twiggs, Houston and Jones). With a population greater than 130,000, this cluster has a five year infant mortality rate of 14.7 infant deaths per 1000 live births, over two times the national average (see Table 2 for detailed population characteristics).
The leading cause of infant death in this cluster was respiratory distress of the newborn accounting for 33 (17.4%) infant deaths. Respiratory distress of newborn was the fifth leading cause of infant death for the state (see Tables 1 and 3).
Causes of death
All causes
Respiratory distress of newborn
Number % of total Mortality
deaths
rate
190 100.0
14.7
33
17.4
2.59
Rank
Disorders related to short 29
15.3
2.28
gestation and low birth
weight, not elsewhere
classified
Congenital malformations, 23
12.1
1.81
chromosomal abnormalities
Rates are infant (under 1 year) deaths per 1,000 live births.
In examining demographic and behavioral factors related to infant death, women who experience an infant death are:
More likely to be 19 years old or younger (24.7% vs. 17.6%) compared to women in the cluster whose infants survive to age 1
Less likely to have more than a high school degree compared to women in the cluster whose infants survive to age 1 (16.8% vs. 29.8%)
Less likely to be White non-Hispanic (20.0% vs. 31.4%) compared to women in the cluster whose infants survive to age 1
Less likely to be married compared to women in the cluster whose infants survive to age 1 (24.3% vs. 32.1%)
More likely to have had previous adverse birth outcomes (2.1% vs. 0.1%) compared to women in the cluster whose infants survive to age 1
Two times less likely to have had adequate prenatal care compared to women in the cluster whose infants survive to age 1 See Tables 4-6 for other data within group comparisons as well as comparisons to the state.
15
Cluster C Muscogee and Chattahoochee
Cluster C covers a portion of 31 census tracts, 7 zip codes, and 2 counties (Muscogee and Chattahoochee). With a population around 118,000, this cluster has a five year infant mortality rate of 15.8 infant deaths per 1000 live births, more than 2.5 times the national average (see Table 2 for detailed population characteristics).
Causes of death
Number % of total Mortality Rank
deaths
rate
All causes
172 100.0
15.8
The three leading causes of infant death within this cluster mirror the leading causes of infant death for the state (see
Disorders related to
77
44.8
7.18
1
short gestation and
low birth weight, not
elsewhere classified
tables 1 and 3), with nearly 45% of the infants dying from
Congenital malformations 20
10.5
1.86
2
and chromosomal
disorders related to preterm birth abnormalities
and low birth weight. These three
leading causes of infant death
Sudden infant
15
8.7
1.40
3
account for more than two-thirds
death syndrome
of infant death in this cluster.
Rates are infant (under 1 year) deaths per 1,000 live births.
In examining demographic and behavioral factors related to infant death, women who experience an infant death are:
More likely to have chronic health conditions when compared to women in the State that also experienced an infant death (28.5% vs. 10.5%)
More likely to be in their teen years (25.0% vs. 18.6%) compared to women in the cluster whose infants survive to age 1
Less likely to have more than a high school degree compared to women in the cluster whose infants survive to age 1 (27.9% vs. 36.0%)
Less likely to be White non-Hispanic (15.7% vs. 27.6%) compared to women in the cluster whose infants survive to age 1
Less likely to be married compared to women in the cluster whose infants survive to age 1 (26.2% vs. 39.9%)
Two times less likely to have had adequate prenatal care compared to women in the cluster whose infants survive to age 1
See Tables 4-6 for other within group comparisons as well as comparisons to the state.
16
Cluster D Lowndes
Cluster D covers a portion of 12 census tracts, 5 zip codes, and 1 county (Lowndes). With a population around 45,000, this cluster has a five year infant mortality rate of 17.5 infant deaths per 1000 live births. This IMR is nearly three times the national average and the highest of all the clusters (see Table 2 for detailed population characteristics).
The three leading causes of infant death within this cluster mirror the leading causes of infant death for the state (see tables 1 and 3), with more than 28% of the infants dying from disorders related to preterm birth and low birth weight.
Causes of death
Number % of total Mortality
deaths
rate
All causes
73
100.0
17.5
Disorders related to
21
short gestation and
low birth weight, not
elsewhere classified
28.8
5.13
Congenital malformations 12
16.4
2.93
and chromosomal
abnormalities
Sudden infant
7
death syndrome
9.6
1.71
Rank 1
2 3
"Women who experience the loss of an infant in this cluster are more likely to have had a Cesarean section or previous poor birth outcome, and are less likely to have a high school degree, be married, or have access to prenatal care."
Rates are infant (under 1 year) deaths per 1,000 live births. In examining demographic and behavioral factors related to infant death, women who experience an infant death are:
Nearly three times less likely to have a chronic health condition compared to women in the cluster whose infants survive to age 1
More likely to have had a Cesarean section than women in the cluster whose infants survive to age 1 (37.0% vs. 28.6%)
Less likely to have more than a high school degree compared to women in the cluster whose infants survive to age 1 (21.9% vs. 31.6%)
. Nearly three times less likely to be White non-Hispanic compared to women in the cluster whose infants survive to age 1
The least likely of all the clusters to be married (35.6%)
More likely to have had previous adverse birth outcomes (1.4% vs. 0.1%) compared to women in the cluster whose infants survive to age 1
Less likely to have had adequate prenatal care (19.2% vs. 30.3%) compared to women in the cluster whose infants survive to age 1
See Tables 4-6 for other within group comparisons as well as comparisons to the state.
17
Cluster E richmond
Cluster E covers a portion of 28 census tracts, 6 zip codes, and 1 county (Richmond). With a population greater than 133,000, this cluster has a five year infant mortality rate of 15.1 infant deaths per 1000 live births, more than two times the national average (see Table 2 for detailed population characteristics).
The three leading causes of infant death within this cluster are the same as the state's, however the order differs. SIDS is the third leading cause of infant death for the state, but the second leading cause of death for this cluster (see tables 1 and 3).
Causes of death
Number % of total Mortality
deaths
rate
All causes
99
100.0
15.1
Disorders related to
20
short gestation and
low birth weight, not
elsewhere classified
20.2
3.09
Rank
1
Sudden infant
14
14.1
2.16
2
death syndrome (SIDS)
Congenital malformations 13
13.1
2.01
3
and chromosomal
abnormalities
Rates are infant (under 1 year) deaths per 1,000 live births.
In examining demographic and behavioral factors related to infant death, women who experience an infant death are:
More likely to have had a Cesarean Section than women in the cluster whose infants survive to age 1 (43.4% vs. 27.6%)
More likely to have less than a high school degree compared to women in the cluster who's infants survive to age 1 (45.5% vs. 32.0%)
Two and a half time less likely to be White non-Hispanic compared to women in the cluster whose infants survive to age 1.)
Less likely to be married compared to women in the cluster whose infants survive to age 1 (15.2% vs. 28.8%)
Two times less likely to have had adequate prenatal care compared to women in the cluster whose infants survive to age 1
See Tables 4-6 for other within group comparisons as well as comparisons to the state.
18
Cluster F chatham
Cluster F covers a portion of 30 census tracts, 9 zip codes, and 1 county (Chatham). With a population nearly 80,000, this cluster has a five year infant mortality rate of 13.3 infant deaths per 1000 live births, more than two times the national average (see Table 2 for detailed population characteristics).
Causes of death
Number % of total Mortality Rank
deaths
rate
All causes
155
100.0
13.3
The three leading causes of
Disorders related to
43
27.7
3.74
1
infant death within this cluster
short gestation and
differ slightly from the state with newborn affected by maternal
low birth weight, not elsewhere classified
complication of pregnancy being
the second leading cause of
Newborn affected by
21
13.5
1.83
2
death for this cluster. It accounts
maternal complications of pregnancy
for 13.5% of infant deaths in this
cluster but only 5.6% of the infant
Congenital malformations, 16
10.3
1.39
3
deaths for the state (see tables
chromosomal abnormalities
1 and 3). SIDS did not make the
top three causes for this cluster.
Rates are infant (under 1 year) deaths per 1,000 live births.
In examining demographic and behavioral factors related to infant death, women who experience an infant death are:
More likely to have chronic diseases than women in the cluster whose infants survive to age 1 (16.8% vs. 12.9%)
More likely to be in their teen years (20.0% vs. 15.5%) compared to women in the cluster whose infants survive to age 1
Less likely to have more than a high school degree compared to women in the cluster who's infants survive to age 1 (40.6% vs. 46.2%)
. Less likely to be White non-Hispanic (18.1% vs. 26.9%) and equally Hispanic (4.5%) compared to women in the cluster whose infants survive to age 1
Less likely to be married compared to women in the cluster whose infants survive to age 1 (29.0% vs. 40.0%)
More likely to be smokers (10.3% vs. 5.9%) compared to women in the cluster whose infants survive to age 1
Two times less likely to have had adequate prenatal care compared to women in the cluster whose infants survive to age 1
See Tables 4-6 for other within group comparisons as well as comparisons to the state.
19
PERINATAL PERIODS OF RISK
The Perinatal Periods of Risk (PPOR) framework aids in understanding where to intervene and what actions are needed to lower a community's feto-infant mortality rate, defined as the number of fetal and infant deaths weighing at least 500 grams and 24 completed gestational weeks divided by the total number of fetal deaths and live births weighing at least 500 grams and 24 completed weeks.
The PPOR framework maps feto-infant mortality by timing of death and birth weight into four categories. A mortality rate is calculated for each category, and is evaluated in terms of a primary prevention focus describing actions and interventions with the goal of reducing the fetal and infant mortality rate. Fetoinfant deaths occurring among those weighing 500 1499 grams are thought to be reduced by interventions related to maternal health and prematurity. Such
interventions could include addressing chronic and infectious diseases before pregnancy and encouraging preconception and interconception health care.
Deaths occurring to fetuses 1500 grams and above are thought to be best prevented by interventions in the maternal care category such as perinatal and prenatal care, as well as high risk referrals. Newborn care category includes neonatal deaths to infants born weighing at least 1500 grams. Interventions to reduce deaths in this category should focus on obstetric care, perinatal management and neonatal care. The infant health category of the PPOR map refers to deaths occurring during the postneonatal period to infants born weighing 1500 grams or more. Initiatives directed at sleep position, injury, breast feeding and pediatric care (surgery) could impact the infant health related mortality rate.
5001499
Places to intervene based upon the PPOR framework
Fetal
Age At Death Neonatal
Postneonatal
Maternal Health / Prematurity
Interventions addressing chronic and infectious diseases before pregnancy and encouraging preconception and interconception care
Birthweight
1500+
Maternal Care
Interventions around quality perinatal and prenatal care as well as high-risk referrals
Newborn Care
Interventions focusing on obstetric care, perinatal management and neonatal care
Infant Health
Interventions addressing sleep position, injury, breastfeeding and pediatric care
20
Figure 1. ppor map
5001499
Fetal
Age At Death
Neonatal
Postneonatal
Maternal Health/Prematurity
Birthweight
1500+
Maternal Care
Newborn Care
Infant Health
Figure 2. Rates for the referent population
Birthweight
5001499
Fetal
Age At Death
Neonatal
Postneonatal
Maternal Health/Prematurity
1.30
1500+
Maternal Care
0.71
Newborn Care
0.34
Infant Health
1.07
21
Cluster A Fulton, Douglas, Cobb and Clayton
In this cluster, nearly 2 deaths per thousand were due to preventable causes like SIDS, unintentional injury and homicide.
Nearly 2 excess deaths per 1000 occurred in the infant health category.
Cluster A has a feto-infant mortality rate of 9.69 per 1000 live births plus fetal deaths, with nearly 5 deaths per 1000 occurring within the maternal health/prematurity category. Excess deaths are seen in all categories, although negligible for newborn care. Of the 5 deaths per 1000 in the maternal health/prematurity category, it is hypothesized that 3.5 deaths per 1000 could be prevented if the feto-infant mortality rate of the referent group were attained by women in this cluster.
Preventable deaths in this category included SIDS deaths (N=40), unintentional injuries (N=10) and homicides (N=4).
To impact the feto-infant mortality rate of this cluster, interventions are needed that address preconception health, intendedness of pregnancies, perinatal health, infant health and safety.
Overall feto-infant mortality rates
Excess feto-infant mortality rates
5001499
Age At Death
Fetal
Neonatal
Postneonatal
Maternal Health/Prematurity 4.82
5001499
Age At Death
Fetal
Neonatal
Postneonatal
Maternal Health/Prematurity 3.52
Birthweight Birthweight
1500+
Maternal Care
1.52
Newborn Care
0.46
Infant Health
2.89
1500+
Maternal Care
0.81
Newborn Care
0.12
Infant Health
1.82
Rates are infant (under 1 year) deaths per 1,000 live births. 22
Cluster B Bibb, Twiggs, Houston and Jones
This cluster mirrors the Fulton, Douglas, Cobb and Clayton cluster in deaths due to preventable causes; however, this cluster has more deaths in the "newborn care" category, suggesting interventions that increase access to quality perinatal care for mother and infant.
"This cluster mirrors the Fulton, Douglas, Cobb, Clayton cluster in deaths due to preventable causes; however, this cluster had more deaths in the "newborn care" category, suggesting interventions that increase access to quality perinatal care for mother and infant."
Cluster B has a feto-infant mortality rate of 11.0 per 1000 live births plus fetal deaths, with nearly 5 deaths per 1000 occurring within the maternal health/prematurity category. Excess deaths are seen in all categories, with nearly 1 per 1000 in newborn care. Of the 5 deaths per 1000 in the maternal health/ prematurity category, it is hypothesized that 3.5 deaths per 1000 could be prevented if the feto-infant mortality rate of the referent group were attained by women in this cluster.
Preventable deaths in this category included SIDS deaths (N=17), unintentional injuries (N=6) and homicides (N=2).
To impact the feto-infant mortality rate of this cluster, interventions are needed that address preconception health, intendedness of pregnancies, perinatal health, infant health and safety.
Birthweight Birthweight
Overall feto-infant mortality rates
Excess feto-infant mortality rates
5001499
Age At Death
Fetal
Neonatal
Postneonatal
Maternal Health/Prematurity 4.87
5001499
Age At Death
Fetal
Neonatal
Postneonatal
Maternal Health/Prematurity 3.57
1500+
Maternal Care
1.96
Newborn Care
1.26
Infant Health
2.91
1500+
Maternal Care
1.25
Newborn Care
0.92
Infant Health
1.84
Rates are infant (under 1 year) deaths per 1,000 live births. 23
Cluster C Muscogee and Chattahoochee
Typically speaking, women are more likely to have a miscarriage of an infant who never reaches 1500 grams than experience the death of an infant weighing more than 1500 grams at birth. In the Muscogee and Chattahoochee cluster however, these rates are very similar: greater than 3 deaths per thousand.
It is rare that the infant health category is as high as the maternal health/ prematurity category, due to the maternal health category including deaths that occur during the fetal, neonatal and
postneonatal periods.
Cluster C has a feto-infant mortality rate of 9.41 per 1000 live births plus fetal deaths, with 3.6 deaths per 1000 occurring within the maternal health/prematurity category. Excess deaths are seen in all categories, with 0.6 per 1000 in newborn care. Of the 3.6 deaths per 1000 in the maternal health/prematurity category, it is hypothesized that 2.3 deaths per 1000 could be prevented if the feto-infant mortality rate of the referent group were attained by women in this cluster.
The infant health cell includes only live births born at a moderate to normal birth weight. In general,
these infants have a greater probability of surviving when compared to the maternal health/prematurity category. In Cluster C, nearly 3.4 deaths per 1000 occurred in the infant health category, preventable deaths in this category included SIDS deaths (N=14), unintentional injuries (N=6) and homicides (N=2).
To impact the feto-infant mortality rate of this cluster, interventions are needed that address preconception health, intendedness of pregnancies, perinatal health, infant health and safety.
Birthweight Birthweight
Overall feto-infant mortality rates
Excess feto-infant mortality rates
5001499
Age At Death
Fetal
Neonatal
Postneonatal
Maternal Health/Prematurity 3.63
5001499
Age At Death
Fetal
Neonatal
Postneonatal
Maternal Health/Prematurity 2.33
1500+
Maternal Care
1.49
Newborn Care
0.93
Infant Health
3.36
1500+
Maternal Care
0.78
Newborn Care
0.59
Infant Health
2.29
Rates are infant (under 1 year) deaths per 1,000 live births. 24
Cluster D Lowndes
The Lowndes cluster has the highest rate of infant mortality with 13.93 deaths per 1,000 live births. With high rates across all categories, a comprehensive approach to intervention is needed.
"While it is uncommon for each cell in the PPOR map to have such high rates of feto-infant mortality, this data supports a comprehensive approach to lowering the
rates in this community."
Cluster D has the highest fetoinfant mortality rate of all the clusters, at 13.93 per 1000 live births plus fetal deaths, with 6.11 deaths per 1000 occurring within the maternal health/prematurity category. Excess deaths are notable in all categories, with 1.12 per 1000 in newborn care. Of the 6.11 deaths per 1000 in the maternal health/prematurity category, it is hypothesized that approximately 5 deaths per 1000 could be prevented if the fetoinfant mortality rate of the referent group were attained by women in this cluster.
To impact the feto-infant mortality rate of this cluster. interventions are needed that address all areas of health that directly impact infant and fetal survival with emphasis on preconception health, intendedness of pregnancies, perinatal health, infant health and safety.
Birthweight Birthweight
Overall feto-infant mortality rates
Excess feto-infant mortality rates
5001499
Age At Death
Fetal
Neonatal
Postneonatal
Maternal Health/Prematurity 6.11
5001499
Age At Death
Fetal
Neonatal
Postneonatal
Maternal Health/Prematurity 4.81
1500+
Maternal Care
2.20
Newborn Care
1.47
Infant Health
4.15
1500+
Maternal Care
1.49
Newborn Care
1.13
Infant Health
3.08
Rates are infant (under 1 year) deaths per 1,000 live births. 25
Cluster E Richmond
The Richmond Cluster has high rates in both maternal health/prematurity and infant health categories, with rates greater than 5 deaths per thousand live births in each.
A similar oddity is occurring with Cluster E as occurred in Cluster C.
Cluster E has a feto-infant mortality rate of 12.34 per 1000 live births plus fetal deaths, with 5.25 deaths per 1000 occurring within the maternal health/prematurity category. Excess deaths are seen mainly in maternal health and prematurity as well as infant health. Of the 5.25 deaths per 1000 in the maternal health/prematurity category, it is hypothesized that nearly 4 deaths per 1000 could be prevented if the feto-infant mortality rate of the referent group were attained by women in this cluster.
Based on the initial PPOR map, the infant health category is as high as the maternal health and prematurity category. However, the excess death for the infant health category is higher than the excess deaths calculated for the maternal health and prematurity cell. To impact the feto-infant mortality rate of this cluster, interventions are needed that address preconception health, intendedness of pregnancies, perinatal health, infant health and safety.
Overall feto-infant mortality rates
Excess feto-infant mortality rates
Birthweight Birthweight
5001499
Age At Death
Fetal
Neonatal
Postneonatal
Maternal Health/Prematurity 5.25
1500+
Maternal Care
1.54
Newborn Care
0.46
Infant Health
5.09
5001499
Age At Death
Fetal
Neonatal
Postneonatal
Maternal Health/Prematurity 3.95
1500+
Maternal Care
0.83
Newborn Care
0.12
Infant Health
4.02
Rates are infant (under 1 year) deaths per 1,000 live births. 26
Cluster F Chatham
SIDS, unintentional injuries and congenital malformations are contributing to this cluster's high infant mortality rate, suggesting interventions are needed to help the mother with her health prior to pregnancy and the familiy's ability to raise children in safe environments.
Infant health issues are among the leading causes of death in the Chatham Cluster.
Cluster F has a feto-infant mortality rate of 8.86 per 1000 live births plus fetal deaths, with more than 4 deaths per 1000 occurring within the maternal health/ prematurity category. Excess deaths are seen in all categories, but are negligible in maternal and newborn care. Of the 4.17 deaths per 1000 in the maternal health/prematurity category, it is hypothesized that 2.9 deaths per 1000 could be prevented if the feto-infant mortality rate of the referent group were attained by women in this cluster.
The incidence of SIDS deaths (N=8), unintentional injuries (N=5) and congenital malformations (N=5) are driving the high infant mortality rate among the infant health cell.
To impact the feto-infant mortality rate of this cluster interventions are needed that address preconception health, intendedness of pregnancies, perinatal health, infant health and safety.
Birthweight Birthweight
Overall feto-infant mortality rates
5001499
Age At Death
Fetal
Neonatal
Postneonatal
Maternal Health/Prematurity 4.17
1500+
Maternal Care
1.04
Newborn Care
0.52
Infant Health
3.13
Excess feto-infant mortality rates
5001499
Age At Death
Fetal
Neonatal
Postneonatal
Maternal Health/Prematurity 2.87
1500+
Maternal Care
0.33
Newborn Care
0.18
Infant Health
2.06
Rates are infant (under 1 year) deaths per 1,000 live births. 27
A Call to Action--Preventing Infant Mortality in Your Community
Following are steps to take to reduce infant mortality in your community, whether within a specific cluster or throughout the state.
Cluster A
Fulton, Douglas, Cobb and Clayton:
Nearly 5 per 1000 deaths were due to maternal health/ prematurity. 3.5/1000 could be prevented with better preconception health, intendedness of pregnancy and perinatal health. 2 deaths per 1,000 were due to preventable causes: SIDS, unintentional injuries, homicide.
Cluster B
Bibb, Twiggs, Houston and Jones:
Nearly 5 per 1000 deaths were due to maternal health/ prematurity. 3.5/1000 could be prevented with better preconception health, intendedness of pregnancy and perinatal health. 1 death per 1,000 was due to preventable causes: SIDS, unintentional injuries, homicide.
Cluster C
Muscogee and Chattahoochee:
3.6 per 1,000 deaths were due to maternal health/prematurity. 2.3/1,000 could be prevented with better preconception health, intendedness of pregnancy and perinatal health. 3.4 per 1,000 deaths were in the infant health category and due to preventable causes: SIDS, unintentional injuries, homicide.
Cluster D
Lowndes:
6.11 per 1000 deaths were due to maternal health/prematurity. 5/1000 could be prevented with better preconception health, intendedness of pregnancy and perinatal health. 1.12 deaths per 1,000 are due to newborn care which could be prevented with better infant health and safety.
Cluster E
Richmond:
5.25 per 1000 deaths were due to maternal health/prematurity. 4/1000 could be prevented with better preconception health, intendedness of pregnancy and perinatal health. 5.09 per 1,000 deaths were due to infant health and indicates a need for communities to address infant health and safety.
Cluster F
Chatham:
4.17 per 1000 deaths were due to maternal health/prematurity. 2.9/1000 could be prevented with better preconception health, intendedness of pregnancy and perinatal health. 3.13 deaths per 1,000 are due to SIDS, unintentional injuries, and congenital malformations. Overall interventions should support preconception health and safe environments.
Preconception refers to health and intendedness of pregnancy refer to the period of time before pregnancy occurs. Perinatal health
is the health of women and babies before, during and after birth. Everyone has a role in reducing infant mortality.
28
What can you do?
Plan your pregnancy--about half of all pregnancies are unplanned.
Address preconception health--take a multi-vitamin pill with 400 mcg of folic acid before getting pregnant to help prevent birth defects.
Stop the use of tobacco or alcohol.
Be healthy-take control of your medical condition, such as diabetes, high blood pressure, asthma, infections or other health problems. Also, be sure that your vaccinations are up to date.
Receive interconception care--wait at least 18 months between pregnancies.
Carry your pregnancy at least 39 weeks whenever possible-- elective deliveries prior to 39 weeks carry significant increased risk of adverse outcomes for your baby.
Enhance infant health and safety--have your baby sleep on his/her back, in a separate sleep space, on a firm mattress.
What can your community do?1
Work to eliminate health disparities and promote health equity. Use data to inform efforts to promote healthy birth outcomes. Implement health promotion and education efforts to
improve birth outcomes. Enhance service integration for women and infants. Improve maternal risk screening for women of reproductive age. Improve access to health care for women before, during
and after pregnancy. Ensure quality of care for all women and infants.
1. AMCHP, 2012
29
METHODS
Data used for this report come mainly from vital statistics and the 2000 census files. Birth and death certificates were matched for infants who died under the age of one year. All analyses were done using the linked birth death file allowing for the evaluation of pregnancy and birth related factors in relation to the infant's death. Infant mortality rates were defined as the number of infants dying before their first birthday divided by the total number of live births during the same period and expressed per 1000 live births. Cohort infant mortality rates were calculated, ensuring that the infants in the numerator were also in the denominator. Infants were excluded from this dataset if their mother was not a resident of the state of Georgia at time of delivery and/or time of death.
Infant mortality was examined at the state level by race/ethnicity, timing of death, and leading causes of infant mortality. Five year average rate ratios were calculated to compare the five year average infant mortality rate
of public health districts to that of the state (IMR of public health district/IMR for state). This analysis was repeated at the county level.
In order to assess the presence of infant mortality clusters that exist outside of administrative boundaries, a fishnet consisting of squares with 1x1 mile cell sizes was created to cover the entire area of the state of Georgia. Based on the geocoded locations of their mother's residence at delivery, all live births in the 2002-2006 birth cohort were aggregated to the one-mile square to obtain the counts of births and deaths observed. The aggregated counts of births and the state's overall infant mortality rate in the years 2002-2006 were used to calculate the expected counts of deaths under the null hypothesis that all births had the same probability of dying in their first year of life. The observed and expected numbers of deaths were then assigned to the centers of the squares, which were used in the creation of the smoothed surface of the standard mortality ratio (SMR) as well as the detection of clusters.
30
The smoothed surface was created using the Spatial Filtering method introduced by Ruston and Lolonis (1996). Centered on the center of each square, a circular area was constructed by expanding the circle from a point to a certain area at which at least 25 expected deaths were captured. The total number of observed deaths within the same area was calculated. The observed and the expected numbers of deaths were then used to calculate SMR by dividing the observed deaths by the expected deaths. The procedure was repeated for all squares. The SMRs were then used to create the smoothed surface.
The clusters were detected using the Spatial Scan Statistic developed by Kulldorff and Nagarwalla (1995). Centered on the center of each square, a set of circles were overlaid with varying radii from 0 to an upper limit defined by a radius of circle that captures a maximum 10% of total births or a maximum of 10 miles. For each circle, the likelihood ratio associated with the ratio of the observed and expected numbers of
deaths inside and outside the circle was calculated. The procedure was repeated for all squares. Then the circles were ranked based on their likelihood ratios. The circle with the maximum likelihood ratio was considered the most likely cluster. For this cluster, it is least likely that the observed number of deaths exceeded the expected number of deaths by chance alone under the null hypothesis that the infant mortality rates inside and outside of the circle were the same. A certain number of other circles were considered secondary clusters. The p-values were obtained for the most likely and the secondary clusters through the Monte Carlo hypothesis testing. Clusters with p-values smaller than 0.05 were said to be statistically significant at an =0.005. This process was repeated using the linked birth death file from 1997 to 2006 to identify clusters of neonatal (deaths occurring before the 28th day of life) and postneonatal (deaths occurring between the 28th day and 364th day of life) deaths. The remainder of the report consists of detailed analyses of the six significant infant mortality clusters.
31
METHODS (CONT'D)
Descriptive Variables
Population-based demographic data was obtained for each cluster using the 2000 Census file. Each cluster was assigned best fit census tracts and population totals were calculated by summing across multiple census tracts. Clusters ranged in size and geography, with the smallest cluster spanning 12 census tracts and the largest spanning 86 census tracts. The availability of physicians was calculated per 1000 population and obtainable only at the county level.
Descriptive and bivariate analyses were preformed for each cluster, due to small numbers, multivariate analyses were not conducted. The three leading causes of infant death were identified for each cluster, along with the number, percentage, and rate of infant death per cause. Medical factors that are known to impact infant health outcomes were examined by cluster for infants who died before their first birthday as well as those who were still living at age one. Similar analyses were conducted for the state as a whole. Birth weight was evaluated as a trichotomous variable, very low birth weight (less than 1500 grams), moderately low birth weight (1500 2499 grams), and normal weight (at least 2500 grams). Gestational age was categorized as less than 28 completed weeks, 28-37 completed weeks, at least 38 completed weeks. Birth defects were considered present if any of the birth defects fields on the birth certificate were positive (anencephaly; cleft lip or palate; club foot; diaphragmatic
hernia; Down's syndrome; heart malformation; hydrocephalus; spina bifida; tracheoesophageal fistula; malformed genitalia; microcephalus; CNS, chromosomal, circulatory, gastrointestinal, musculoskeletal, or urogenital anomalies; rectal atresia; or renal agenesis). Maternal chronic diseases included the presence of one or more of the following: acute or chronic lung disease, anemia, cardiac disease, pregnancy associated or chronic diabetes and hypertension, hemoglobinopathy and/or renal disease. Infectious disease of the mother included one or more of the following: herpes, rubella and/or syphilis. Cesarean section included primary and secondary cesarean sections.
Maternal demographic factors that are known to impact infant health outcomes were examined by cluster for infants who died before their first birthday as well as those who were still living at age one. Similar analyses were conducted for the state as a whole. Maternal age was categorized as less than or equal to 19, 20-34, 35 and greater; maternal education as less than high school; high school completion; greater than high school; maternal race/ethnicity as White non-Hispanic; Black nonHispanic; Other non-Hispanic; and Hispanic; marital status as unmarried or married.
Maternal behavioral factors known to be associated with infant health outcomes were examined by cluster for infants who died before their first birthday as well as those who were still living at age one. Similar analyses were conducted for the state as a whole. Smoking and alcohol use were evaluated as
32
dichotomous variables (yes/ no), previous adverse birth outcome was a composite variable and considered present if any of the following were present- previous low birth weight, preterm birth and/or small for gestational age. Adequacy of prenatal care was examined using the Kotelchuck index which takes into account number of prenatal visits and month of prenatal care initiation. Interpregnancy interval was categorized as six months or less, seven to 17 months, 18 months or more.
The Perinatal Periods of Risk framework aids in understanding where to intervene and what actions are needed to lower a community's feto-infant mortality rate. Fetal death files from 2002-2006 were appended to the linked birth death certificate file to calculate feto-infant mortality rates, defined as the number of fetal and infant deaths weighing at least 500 grams and 24 completed gestational weeks divided by the total number of fetal deaths and live births weighing at least 500 grams and 24 completed weeks during the same time period. Feto-infant mortality rates were expressed per 1000 live births and fetal deaths. This definition was chosen in compliance with the perinatal periods of risk model.
The PPOR framework maps feto-infant mortality by timing of death and birth weight into four categories. A mortality rate is calculated for each
category, and is evaluated in terms of a primary prevention focus describing actions and interventions with the goal of reducing the fetal and infant mortality. Feto-infant deaths occurring among those weighing 500 1499 grams are thought to be reduced by interventions related to maternal health and prematurity. Such interventions could include addressing chronic and infectious diseases before pregnancy and encouraging preconception and interconception health care.
Deaths occurring to fetuses 1500 grams and above are thought to be best prevented by interventions in the maternal care category such as perinatal and prenatal care, as well as high risk referrals. Newborn care category includes neonatal deaths to infants born weighing at least 1500 grams. Interventions to reduce deaths in this category should focus on obstetric care, perinatal management and neonatal care. The infant health category of the PPOR map refers to deaths occurring during the postneonatal period to infants born weighing 1500 grams or more. Initiatives directed at sleep position, injury, breast feeding, and pediatric care (surgery) could impact the infant health related mortality rate.
33
Table 2. Demographic characteristics for the six geographical clusters of infant mortality in GA, 2002-2006
data tables
Public Health Districts Encompassing counties # of Census Tracts population % Poverty % White % HS Grad Obgyns /1000 of female pop Pediatric Docs /1000 of total pop # MDs/ 1000 of total pop IMR
Clusters A
Clayton
CobbDouglas
Fulton
Fulton, Douglas, Cobb, Clayton
Bibb, Twiggs,
B
North Central
Houston,
Jones
C
West Central
Muscogee, Chatahoochee
D
South
Lowndes
East
E
Central
Richmond
86
359,081
23.1 11.8 74.1 0.48 0.23 6.9 11.8
36
133,729
23.9 39.5 70.8 0.42
0.18
5.4 14.7
31
117,942
19.9 34.4 75.9 0.22
0.12
5.4 15.8
12
45,384
26.2 48.2 68.3 0.24 0.09 3.7 17.5
28
133,296
23.8 38.5 73.4 0.61
0.41 10.6 15.1
F
Coastal
Chatham
30
79,481
25.8 27.2 67.9 0.47 0.27 6.9 13.3
Georgia
All
1618 8,186,453 13.0 65.1 78.6 0.30
0.17
Approximate population totals are calculated from census tract level data. Best fit census tracts were assigned to the clusters. Where necessary, population totals were calculated by adding multiple census tracts together.
IMR--infant mortality rate expressed per 1000 live births
2.2 8.24
34
Table 3. Top three leading causes of infant death for each geographical cluster GA, 2002-2006
data tables
Clusters Cause of death
Number
% of total deaths
All Causes
337
100.0
Disorders related to short gestation and LBW, not elsewhere classified
69
A
Congenital malformations, chromosomal abnormalities
50
20.5 14.8
Sudden infant death syndrome
42
12.5
All Causes
190
100.0
Respiratory distress of newborn
33
17.4
B
Disorders related to short gestation and LBW, not elsewhere classified
29
15.3
Congenital malformations, chromosomal abnormalities
23
12.1
All Causes
172
100.0
Disorders related to short gestation and LBW, not elsewhere classified
77
C
Congenital malformations, chromosomal abnormalities
20
44.8 10.5
Sudden infant death syndrome
15
8.7
All Causes
73
100.0
Disorders related to short gestation and LBW, not elsewhere classified
21
D
Congenital malformations, chromosomal abnormalities
12
28.8 16.4
Sudden infant death syndrome
7
9.6
All Causes
99
100.0
Disorders related to short gestation and LBW, not elsewhere classified
20
E
Sudden infant death syndrome
14
20.2 14.1
Congenital malformations, chromosomal abnormalities
13
13.1
All Causes
155
100.0
Disorders related to short gestation and LBW, not elsewhere classified
43
27.7
F
Newborn affected by maternal complications of pregnancy
21
13.5
Congenital malformations, chromosomal abnormalities
16
10.3
Rates are infant (under 1 year) deaths per 1,000 live births; LBW = Low Birth Weight
Mortality Rate
11.8 2.44
1.77 1.49 14.7 2.59 2.28
1.81 15.8 7.18
1.86 1.40 17.5 5.13
2.93 1.71 15.1 3.09 2.16 2.01 13.3 3.74
1.83
1.39
Rank
.... 1
2 3 ... 1 2
3 ... 1
2 3 ... 1
2 3 ... 1 2 3 ... 1
2
3
35
Table 4. State level and Sub-county level analyses of medical factors associated with infant death, GA, 2002-2006
data tables
Birth weight <1500 grams
1500-2499 grams
2500 grams Gestational Age
<28 weeks
28-37 weeks
Geographical Cluster
Cluster
% infant deaths
% live births living at 1yr
A
59.3
B
58.9
C
64.0
D
56.2
E
53.5
F
65.2
A
10.7
B
19.5
C
11.0
D
15.1
E
14.1
F
10.3
A
30.0
B
21.6
C
25.0
D
28.8
E
32.3
F
24.5
2.1 1.9 1.7 1.5 2.0 1.6 10.5 10.3 9.4 9.5 9.6 9.3 87.4 87.8 88.9 89.0 88.5 89.0
A
51.9
B
52.1
C
60.5
D
49.3
E
48.5
F
59.4
A
26.7
B
27.4
C
24.4
D
24.7
E
26.3
F
22.6
0.9 0.6 0.7 0.7 0.7 0.6 27.4 28.4 24.4 26.7 25.5 26.1
Georgia
% infant deaths
% live births living at 1yr
56.1
1.3
13.6
7.4
30.2
91.2
48.5
0.5
26.7
22.7
36
data tables COnt'd
38+ weeks
Birth Defects
Maternal Chronic Diseases
Maternal Infectious Diseases
Cesarean Section
Geographical Cluster
Cluster
A B C D E F A B C D E F A B C D E F A B C D E F A B C D E F
% infant deaths
21.4 20.5 15.1 26.0 25.3 18.1 6.8 11.1 10.5 6.8 2.0 5.2 10.1 5.8 28.5 1.4 9.1 16.8 0.0 0.5 0.0 0.0 1.0 0.0 35.0 25.3 24.4 37.0 43.4 29.7
% live births living at 1yr
71.7 70.9 74.9 72.6 73.8 73.3 0.3 0.3 0.9 0.3 0.3 0.8 8.8 4.9 22.4 3.9 6.2 12.9 1.8 0.6 1.9 1.3 1.4 1.4 26.4 27.1 28.1 28.6 27.6 35.5
Georgia
% infant deaths
% live births living at 1yr
24.9
76.8
9.4
0.6
10.5
8.3
0.9
1.3
36.2
28.8
Birth Defects include all congenital anomalies collected in the birth certificate.
Chronic diseases include: Acute or Chronic Lung Disease, Anemia HCT less than 30 HGB less than 10, Cardiac Disease, Pregnancy associated and chronic diabetes and hypertension, Hemoglobinophathies, and Renal disease.
Infectious diseases present in the mother include: Herpes, Rubella, and Syphilis.
37
Table 5. State level and Sub-county level analyses of demographic factors associated
data tables
Label
Maternal Age
A
B
C
19
D
E
F
A
B
C
20-34
D
E
F
A
B
C
35
D
E
F
Maternal Education
A
B
C
< High School
D
E
F
A
B
High School
C
Grad
D
E
F
A
B
C
> High School
D
E
F
38
Geographical Cluster
% infant deaths
% live births living at 1yr
18.4 24.7 25.0 16.4 19.2 20.0 73.9 69.5 64.5 79.5 75.8 73.5 7.7 5.8 10.5 4.1 5.1 6.5
16.2 17.6 18.6 19.7 18.8 15.5 73.9 75.7 75.3 75.1 74.9 76.5 9.8 6.7 6.1 5.2 6.2 7.9
27.3 36.3 29.7 30.1 45.5 16.1 37.7 42.6 40.7 41.1 27.3 41.3 24.9 16.8 27.9 21.9 27.3 40.6
30.6 25.8 26.0 29.1 32.0 19.2 34.4 42.5 37.8 38.1 35.2 33.7 31.8 29.8 36.0 31.6 32.6 46.2
Georgia
% infant deaths
% live births living at 1yr
16.7
12.0
71.9
75.8
11.5
12.1
26.5
23.8
33.7
29.8
32.2
43.6
data tables COnt'd
Geographical Cluster
Cluster
% infant deaths
% live births living at 1yr
Maternal Race/Ethnicity
A
1.5
4.8
B
20.0
31.4
White non-
C
15.7
27.6
Hispanic
D
16.4
34.0
E
9.1
24.5
F
18.1
26.9
A
91.4
80.2
B
77.4
61.1
Black non-
C
75.0
61.8
Hispanic
D
76.7
58.4
E
87.9
71.1
F
74.2
65.6
A
0.6
1.6
B
0.5
1.6
Other non-
C
4.1
2.5
Hispanic
D
4.1
1.6
E
1.0
1.4
F
0.6
2.6
A
4.5
11.7
B
1.6
3.9
C
4.1
7.6
Hispanic
D
2.7
5.3
E
2.0
2.6
F
4.5
4.5
Marital Status
A
75.7
67.9
B
75.8
62.4
C
73.8
60.0
Unmarried
D
64.4
59.3
E
84.8
71.2
F
71.0
60.0
A
24.3
32.1
B
24.2
37.6
C
26.2
39.9
Married
D
35.6
40.7
E
15.2
28.8
F
29.0
40.0
Georgia
% infant deaths
% live births living at 1yr
34.1
48.1
49.7
31.3
2.6
3.7
9.5
14.4
55.2
39.6
44.6
60.4
39
data tables
Smoking
Alcohol
Previous Adverse Birth
Outcome Parity
1
2 to 4
Table 6. State level and Sub-county level analyses of behavioral risk factors associated with infant death, GA, 2002-2006
Geographical Cluster
Georgia
ClusteR
% infant deaths
% live births living at 1yr
% infant deaths
% live births living at 1yr
A
5.9
3.8
B
7.4
10.7
C
12.2
10.5
11.1
7.4
D
8.2
6.9
E
9.1
9.9
F
10.3
5.9
A
0.9
0.6
B
0.5
0.5
C
3.5
1.5
1.0
0.6
D
0.0
0.3
E
1.0
0.8
F
1.9
1.0
A
2.1
0.7
B
2.1
0.1
C
0.6
0.6
1.7
0.6
D
1.4
0.1
E
0.0
0.0
F
0.6
0.2
A
36.8
B
39.5
C
41.3
D
37.0
E
35.4
F
44.5
A
51.3
B
47.4
C
44.8
D
45.2
E
51.5
F
40.0
38.0 38.3 38.6 40.5 36.4 39.6 53.3 53.8 55.8 53.4 55.9 53.7
40.4 47.2
39.8 55.0
40
data tables COnt'd
Geographical Cluster
Cluster
% infant deaths
% live births living at 1yr
A
5.0
7.0
B
6.3
6.2
C
5.2
4.0
5+
D
11.0
5.0
E
5.1
6.2
F
5.2
5.0
Prenatal Care (Kotelchuck index)
A
24.3
20.4
B
11.6
7.0
C
21.5
22.0
Inadequate
D
17.8
12.9
E
11.1
14.5
F
23.9
23.3
A
7.7
13.9
B
11.6
14.8
C
10.5
18.1
Intermediate
D
2.7
17.5
E
12.1
22.2
F
11.0
17.3
A
16.3
34.1
B
28.4
42.4
C
15.7
31.0
Adequate
D
19.2
30.3
E
18.2
36.8
F
22.6
35.2
A
38.9
26.0
B
42.6
34.3
C
50.0
27.2
Adequate Plus
D
39.7
30.3
E
57.6
26.1
F
34.8
22.3
Georgia
% infant deaths
% live births living at 1yr
4.8
3.6
14.6
11.5
8.7
14.0
21.7
39.0
47.1
31.8
41
Table 6. State level and Sub-county level analyses of behavioral
risk factors associated with infant death, GA, 2002-2006
data tables COnt'd
Geographical Cluster
Cluster
% infant deaths
% live births living at 1yr
Georgia
% infant deaths
% live births living at 1yr
Interpregnancy interval
A
0.3
0.0
B
0.0
0.0
C
1.2
0.0
6 months
0.3
0.0
D
0.0
0.0
E
0.0
0.0
F
1.3
0.0
A
9.2
7.7
B
8.9
9.1
C
10.5
8.0
7-17 months
8.9
6.5
D
12.3
7.6
E
9.1
10.7
F
9.7
9.5
A
32.6
39.4
B
34.2
44.8
18+
C
33.1
D
30.1
46.0 33.8
32.9
44.0
E
47.5
49.7
F
27.1
44.6
Previous adverse birth outcome includes low birth weight, preterm, and small for gestational age Parity is the number of live births a woman has had in her reproductive career, including current delivery
42
Definition of Terms
Fetal death--Deaths occurring to fetuses weighing at least 500 grams and 24 completed gestational weeks.
Feto-infant mortality rate--The number of fetal deaths (the death of a fetus before complete expulsion from its mother at 500 grams and at least 24 weeks gestation) plus the number of infant deaths (death of a live born baby before completing 365 days of life. ) divided by the total number of fetal deaths plus live births and expressed as a rate per 1,000.1
Intendedness of pregnancy--The extent to which a pregnancy is planned or intended. Current studies suggest that as many as half of all pregnancies are unplanned, leading to higher frequencies of conceptions among women without preconception care.
Interconception care--Care given to women between pregnancies. The main goal of interconception care is to provide health promotion, screening and interventions for women following a pregnancy to ensure the best health outcomes of subsequent pregnancies.
Neonatal--The period from birth to 27 days of age.
Perinatal periods of risk--Fetal and infant death rates organized by intervention strategies (Women's health, maternal care, newborn care, and infant care) in order to facilitate local health planning.2
Preconception care--Care given to women before they are pregnant. According to the Centers for Disease Control and Prevention, the main goal of preconception care is to provide health promotion, screening and interventions for women of reproductive age to reduce risk factors that might affect future pregnancies.3
Prenatal--The period that spans a woman's pregnancy.
Postneonatal--The period from 28 days after birth through 364 days of age.4
1. http://oasis.state.ga.us/oasis/oasis/help/infantdeathwppor.html 2. http://oasis.state.ga.us/oasis/oasis/help/infantdeathwppor.html 3. http://www.cdc.gov/ncbddd/preconception/ 4. http://oasis.state.ga.us/oasis/oasis/help/infantdeathwppor.html
43
Georgia Department of Public Health 2 Peachtree Street, NW 15th Floor Atlanta, Georgia 30303
www.health.state.ga.us/publications