- Collection:
- Atlanta University and Clark Atlanta University Theses and Dissertations
- Title:
- Characterization of Pyrazinamide mono-resistant strains of Mycobacterium Tuberculosis complex isolates submitted to centers for disease control from United States public health laboratories for drug susceptibility testing, 2011
- Creator:
- Franklin, Jameelah Atiya
- Date of Original:
- 2011-05-01
- Subject:
- Degrees, Academic
Dissertations, Academic - Location:
- United States, Georgia, Fulton County, Atlanta, 33.749, -84.38798
- Medium:
- theses
- Type:
- Text
- Format:
- application/pdf
- Description:
- Pyrazinamide (PZA) is an important first line drug for the treatment of tuberculosis. While isolates of Mycobacterium bovis are intrinsically resistant to PZA and susceptible to all other anti-tuberculosis drugs, Mycobacterium tuberculosis isolates resistant to PZA are usually resistant to other first line anti-tuberculosis drugs as well. However, rare strains of M tuberculosis resistant only to PZA have been described in a previous study. Recently, methodological problems with PZA testing have been described previously, and Centers for Disease Control and Prevention (CDC) has recognized an increase in submission of PZA mono-resistant M. tuberculosis isolates from US public health labs.
- External Identifiers:
- Metadata URL:
- http://hdl.handle.net/20.500.12322/cau.td:2011_franklin_jameelah_a
- Rights Holder:
- Clark Atlanta University
- Holding Institution:
- Atlanta University Center Robert W. Woodruff Library
- Rights:
-
