A Pediatric Guide 
Caring for Infants BorntoHepatitisBInfectedMothers 
 
AGE Birth (Within 12 hours) 1-2 Months 6 Months 
9-18 Months 
 
INTERVENTION 
Hepatitis B Immune Globulin (HBIG) AND Hepatitis B Vaccine Dose #1 
Hepatitis B Vaccine Dose #2* 
Hepatitis B Vaccine Dose #3 
Post Vaccination Serologic Testing (PVT) (HBsAg and anti-HBs) 
Blood for the PVT should not be drawn before 9 months of age AND must be drawn a minimum of 30 days after final hepatitis B vaccine. 
*Low Birth Weight Infants (less than 4.4 lbs or 2,000 grams) should receive 4 doses of hepatitis B vaccine. The schedule for low birth weight infants is: HBIG & hepatitis B vaccine at birth, hepatitis B vaccine at 1 month, 2 months and 6 months. 
 
Interpretation of PVT Results 
 
Positive 
 
Hepatitis B Surface Antigen 
(HBsAg) 
 
Infected. Report to Public Health. No additional vaccine 
needed. 
 
Negative 
 
Hepatitis B Surface Antibody 
(anti-HBs) 
 
Negative 
Not Infected 
Positive 
Immune to hepatitis B 
 
No Immunity 
 
Send all PVT results to your district Perinatal Hepatitis B Case Manager. 
 
Georgia Department of Public Health 
For more information or to locate your district case manager, visit the Georgia Department of Public Health's Perinatal Hepatitis B Prevention Program website at 
www.dph.georgia.gov/perinatal-hepatitis-b.