Acid phosphatase activity, in the liver of larval and adult frogs following treatment with carbon tetrachloride, 1967

Collection:
Atlanta University and Clark Atlanta University Theses and Dissertations
Title:
Acid phosphatase activity, in the liver of larval and adult frogs following treatment with carbon tetrachloride, 1967
Creator:
Davis, Ruthanne
Contributor to Resource:
Hunter, Roy
Date of Original:
1967-08-01
Subject:
Degrees, Academic
Dissertations, Academic
Location:
United States, Georgia, Fulton County, Atlanta, 33.749, -84.38798
Medium:
dissertations
theses
Type:
Text
Format:
application/pdf
Description:
Degree Type: thesis
Degree Name: Master of Science (MS)
Date of Degree: 1967
Granting Institution: Atlanta University
Department/ School: Department of Biology
The liver in both larval and adult frogs treated with carbon tetra-chloride was studied for general tissue damage and acid phosphatase activity. The animals sacrificed 2k hr after injection of carbon tetra-chloride and olive oil showed a marked acid phosphatase reaction. This enzymatic activity was localized in granular bodies predominantly along the bile canaliculi and also in the Kupffer cells. The control livers and those treated with olive oil only did not give a positive acid phosphatase reaction. The presence of a high acid phosphatase activity 2k hr after treatment with carbon tetrachloride suggested that tissues had been damaged. This observation was in keeping with the proposal that the hydrolytic enzymes contained within the lysosomal bodies of these cells had been released, in this instance by carbon tetrachloride poisoning.
Metadata URL:
http://hdl.handle.net/20.500.12322/cau.td:1967_davis_ruthanne
Language:
eng
Holding Institution:
Clark Atlanta University
Rights:
Rights Statement information

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